|
名稱 |
Rat TNF-alpha / TNFA Protein/重組大鼠TNF-alpha / T |
|
規格 |
20ug |
|
編號 |
CZDB-004 |
|
價格 |
詢價 |
|
中文名 |
Rat TNF-alpha / TNFA Protein/重組大鼠TNF-alpha / T |
|
分子別稱 |
TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2 |
|
分子種屬 |
Rat |
|
表達標簽 |
His，S |
|
表達宿主 |
E. coli |
|
濃度 |
> 95 % as determined by SDS-PAGE |
|
緩沖液 |
Lyophilized from sterile PBS, pH 7.4 |
|
存儲條件 |
-70°C，應避免反復凍融。 |
|
基本描述 |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment. |
